Patent · US Expired

Double-ended tube for separating phases of blood

US5354483A · kind A · utility

103Cited by
47References
5Claims
0Family size

Assignee

Inventor

Key dates

Filing dateOct 1, 1992
Grant dateOct 11, 1994
Priority date
Expiry dateOct 1, 2012

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01D2221/10
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

A method of partitioning a pre-selected phase of a sample of liquid having a plurality of phases of differing densities, a separating element and a tube containing the separating element. The sample of liquid is placed in a first chamber of a tube that is separated from a second chamber by a separating element. The separating element slidably engages the interior surface of the tube in a substantially fluid-tight manner. A fluid passage is disposed through the separating element and includes an initially closed fluid passage. The phases are ordered by axial centrifugation wherein the tube is rotated about its longitudinal axis, the separating element is moved within the tube reducing the volume of the first chamber, a pre-selected phase of the liquid is forced from the first chamber through the fluid passage into a second chamber. The reduction of the volume of the first chamber is controlled using phase-separation information. The separator may also include a filter for filtering the fluid. The method is useful in the separation of blood components.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.