Process for producing solid active substance forms and products thereof

US5354561A · kind A · utility

Assignee

• Knoll, Inc. · DE

Inventors

• Joerg Rosenberg · Ellerstadt, DE
• Juergen Heberger · Schifferstadt, DE

Key dates

• Filing date: Aug 19, 1992
• Grant date: Oct 11, 1994
• Expiry date: Aug 19, 2012

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/146
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A process is described for the production of solid forms of active substances, which forms have good redispersibility in aqueous systems, which comprises mixing PEG and dextran with water and--if phase separation occurs--removing the upper phase, dissolving an active substance in the mixture, where appropriate adding a physiologically tolerated amphiphile, and subsequently removing the water.