Monoclonal antibody to enterohemorrhagic Escherichia coli 0157:H7 and 026:H11 and method for detection
US5354661A · kind A · utility
12Cited by
2References
20Claims
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Key dates
| Filing date | May 26, 1992 |
| Grant date | Oct 11, 1994 |
| Priority date | — |
| Expiry date | May 26, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/825
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A monoclonal antibody specific for enterohemorrhagic Escherichia coli 0157:H7 and 026:H11 is produced by immunizing BALB/c mice with a strain of E. coli 0157:H7. The antibody reacts strongly by an enzyme-linked immunosorbent assay with an approximately 5,000-6,000 dalton molecular weight outer membrane protein of strains of enterohemorrhagic Escherichia coli 0157:H7 and 026:H11. A rapid and sensitive assay for detecting these organisms is also disclosed.
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