Patent · US Expired

Squaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use

US5354746A · kind A · utility

9Cited by
26References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 1, 1993
Grant dateOct 11, 1994
Priority date
Expiry dateJun 1, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D267/20
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides substituted dibenzoxazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, and as prostaglandin-E.sub.2 antagonists for the treatment of prostaglandin-E.sub.2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal, and a method for treating prostaglandin-E.sub.2 mediated diseases in an animal, comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.