Patent · US Expired

Benzene derivatives, their preparation and pharmaceutical compositions in which they are present

US5354781A · kind A · utility

5Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 24, 1991
Grant dateOct 11, 1994
Priority date
Expiry dateMay 24, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds of the formula ##STR1## in which: p1 R.sub.1 is hydrogen or a halogen atom; R.sub.2 is a cyclohexyl or a phenyl; PA1 R.sub.3 is a (C.sub.3 -C.sub.6) cycloalkyl; PA1 R.sub.4 is hydrogen, (C.sub.1 -C.sub.6) alkyl or (C.sub.3 -C.sub.6)cycloalkyl; PA1 A is --CO--CH.sub.2 --, --CH(CI)--CH.sub.2 --, --CH(OH)--CH.sub.2 --, CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- and --C.tbd.C--, or their addition salt with mineral or organic acids. These compounds are active on the immune system. The present invention further relates to a method of preparing said compounds and to the pharmaceutical compounds in which they are present.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.