Biocompatible metal surfaces
US5356433A · kind A · utility
447Cited by
14References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 3, 1993 |
| Grant date | Oct 18, 1994 |
| Priority date | — |
| Expiry date | Nov 3, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/901
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Metallic surfaces of medical devices or components of medical devices are provided that have enhanced biocompatibility properties. The surfaces are prepared by a two-step procedure including covalently linking an organosilane having amine reactive sites with the surface of the metallic member, typically through a metal oxide thereof. Thereafter, a biologically active agent is covalently linked to the organosilane coating. The two-step process is particularly advantageous for preparing medical devices in the form of stents which need to be bent and flexed during implantation procedures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.