Carbohydrate glass matrix for the sustained release of a therapeutic agent
US5356635A · kind A · utility
82Cited by
7References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 13, 1993 |
| Grant date | Oct 18, 1994 |
| Priority date | — |
| Expiry date | Jul 13, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2018
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition for the sustained release of a biologically active therapeutic agent wherein the matrix of the sustained release composition is composed of an amorphous carbohydrate glass matrix comprising a suitable carbohydrate and an agent which retards the recrystallization of the carbohydrate and a biologically active therapeutic agent and a water-insoluble wax dispersed throughout the matrix. Biologically active therapeutic agents which can be incorporated into the carbohydrate glass matrix include prolactin, growth hormones, serum albumins, growth factors or any biologically active fragment or recombinant form thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.