Membrane expression of heterologous genes
US5356797A · kind A · utility
14Cited by
1References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 15, 1991 |
| Grant date | Oct 18, 1994 |
| Priority date | — |
| Expiry date | Nov 15, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16122
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to nucleic acid segments useful in the construction of expression vectors for expression of heterologous polypeptides directed to particular areas of the host cell. Selected constructs direct production of polypeptides to the outer membrane surface of the cell. Other constructs direct expression of heterologous polypeptides to the inner membrane/periplasm of the host cell. Transformed host cells are potentially useful for the production of vaccines or immunogens elicited in response to antigens expressed on the outer membranes of the host cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.