Patent · US Expired

Cytotoxic agents

US5356928A · kind A · utility

16Cited by
1References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 17, 1993
Grant dateOct 18, 1994
Priority date
Expiry dateSep 17, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H15/256
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to pharmaceutical compositions comprising an effective cytotoxic amount of: ##STR1## Wherein R represents Ac or H; R' represents: ##STR2## OH; and R" represents: ##STR3## these new compounds demonstrate surprising tubulin binding activity and cytotoxicity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.