Synthetic peptides capable of eliciting fibrin-specific monoclonal antibodies lacking fibrinogen-cross-reactivity
US5357042A · kind A · utility
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8References
4Claims
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Key dates
| Filing date | Aug 24, 1992 |
| Grant date | Oct 18, 1994 |
| Priority date | — |
| Expiry date | Aug 24, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Peptides comprising fibrin-specific epitopic sequences are used to prepare hybridoma cell lines producing antifibrin-specific monoclonal antibodies substantially devoid of fibrinogen-cross-reactivity obtained by somatic cell fusion. The antibodies are useful for the in vivo and in vitro detection of thrombi and fibrin deposits.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.