Nonantigenic keratinous protein material
US5358935A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 19, 1992 |
| Grant date | Oct 25, 1994 |
| Priority date | — |
| Expiry date | Nov 19, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/901
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is a new nonantigenic keratinous protein material that may be used as a number of purposes, including correction of soft tissue deficiencies and the creation of biomedical implants and implant coatings. The present invention also includes processes for using the nonantigenic keratinous protein material for soft tissue augmentation, creating implants, and the coating of biocompatible implants. The nonantigenic keratinous protein material can be formed by obtaining nonantigenic keratinous protein and processing it to a powder form. If hair from the recipient or a compatible doner is used, it is bleached and rinsed, then dried and chopped into about 0.25 inch pieces. The keratinous protein is then homogenized in a solvent to a particular size generally in the range of about 0.1 to about 500 .mu.m. The particles are then ultrasonicated in a solvent. Afterwards, the solvent is evaporated, and the powdered protein is sterilized and suspended in a sterile bioinert solvent to create a protein colloid at a solids concentrations suitable for injection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.