Patent · US Expired

Aqueous film-forming compositions for controlling the release of active agents

US5358990A · kind A · utility

9Cited by
13References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 11, 1993
Grant dateOct 25, 1994
Priority date
Expiry dateFeb 11, 2013

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/2853
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Aqueous coating compositions for forming elastomeric films around active cores (e.g., drugs) comprising a dispersion of pre-crosslinked polyorganosiloxane latex particles, colloidal silica particles, and a water-dispersible organic material (e.g., polyethylene glycol) are disclosed and claimed. The elastomeric films formed by the coating compositions are used to control the rate of release of an active agent in the cores into an aqueous environment. Methods of formulating the coating compositions and active cores coated with the coating compositions are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.