Unsymmetrical bis-imides as anticancer agents
US5359070A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 11, 1993 |
| Grant date | Oct 25, 1994 |
| Priority date | — |
| Expiry date | Feb 11, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to unsymmetrical bis-imide compounds, and pharmaceutically acceptable salts thereof, of the formula (i): ##STR1## including (R,R)-1-[2-(acenaphthene-5,6-dicarboximido) propylamino]-2-[2-(3-nitronaphthalene-1,8-dicarboximido) propylamino]ethane, processes for the preparation of such compounds, pharmaceutical compositions containing such compounds, and methods of using such compounds to treat cancer, particularly solid tumor carcinomas, in mammals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.