Glycine derivative monosodium salt tetrahydrate
US5359121A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 18, 1994 |
| Grant date | Oct 25, 1994 |
| Priority date | — |
| Expiry date | Jan 18, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C311/29
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
N-[o-(p-pivaloyloxybenzenesulfonylamino)benzoyl]glycine monosodium salt tetrahydrate of the formula (I): ##STR1## is non-hygroscopic, homogeneous and stable compound, and has an inhibitory effect on elastase. Accordingly, the compound may be useful for the treatment and/or prevention of diseases induced by the abnormal enhancing of degradation of elastin, collagen fiber and/or proteoglican by the action of elastase, e.g., pulmonary emphysema, atherosclerosis, rheumatoid arthritis, etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.