Polysubstituted benzimidazoles as antiviral agents
US5360795A · kind A · utility
30Cited by
14References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 21, 1992 |
| Grant date | Nov 1, 1994 |
| Priority date | — |
| Expiry date | Oct 21, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel polysubstituted benzimidazoles and compositions and their use in the treatment of viral infections. The polysubstituted benzimidazoles and compositions of the present invention exhibit antiviral properties against viruses of the herpes family, particularly human cytomegalovirus (HCMV) and herpes simplex viruses (HSV). Preferred polysubstituted benzimidazoles of the invention are 2,5,6-Trichloro-1-(.beta.-D-5-deoxyribofuranosyl)benzimidazole and 2-bromo-5,6-dichloro-1-(5-deoxy-.beta.-D-ribofuranosyl)benzimidazole.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.