Method for detecting and locating inflammatory or tumor foci in a patient and diagnostic kit therefor
US5362474A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 8, 1992 |
| Grant date | Nov 8, 1994 |
| Priority date | — |
| Expiry date | Jul 8, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an aerosol composition containing a carrier agent capable of recognizing and binding to inflammatory and tumor foci mobilizing macrophages in their immediate environment, and an aerosol substrate, characterized in that the said carrier agent consists of a polysaccharide compound selected from the compound D 25, extracted from the membrane proteoglycans of the bacterium Klebsiella pneumoniae and having a molecular weight of 30.+-.0.10 Kd, and the compound oxidized D 25 in which the galactofuranoser residue (Gal.sub.f) of the linear polysaccharide chain of D 25 has been converted to arabinose, and their amide, ester or ether type derivatives, as well as their quaternary ammonium derivatives and salts, and also the derivatives obtained by grafting of phosphatides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.