Alkyl phosphonate polyazamacrocyclic cheates for MRI
US5362476A · kind A · utility
8Cited by
22References
6Claims
0Family size
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Inventors
Key dates
| Filing date | Jul 31, 1992 |
| Grant date | Nov 8, 1994 |
| Priority date | — |
| Expiry date | Jul 31, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a new polyazamacrocyclic compound or a salt thereof and its uses as a tissue specific chelator. The compound has the formula ##STR1## where x is 2, 3 or a combination of p 2(s) and q 3(s) where p+q=y; PA0 y is 4; PA0 R is ( CH.sub.2).sub.z P(=0)OR.sup.1 OR.sup.2 ; PA0 R.sup.1 is H or CH.sub.3 ; PA0 R.sup.2 is C.sub.n H.sub.1+2n ; PA0 n is 4 to 6; PA0 z is 1 to 3. PA0 M is a heavy metal ion. These compounds may be used for magnetic resonance imaging.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.