Oral hygiene compositions containing amino sugars as antiplaque agents

US5362480A · kind A · utility

Assignee

• Lever Brothers Company, division of Conopco, Inc. · US

Inventors

• Van Au · Oxford, US
• Robert Carson · Rahway, US
• Bijan Harirchian · South Orange, US
• Kurt Schilling · Schwetzingen, DE

Key dates

• Filing date: Nov 25, 1992
• Grant date: Nov 8, 1994
• Expiry date: Nov 25, 2012

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P1/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Oral hygiene antiplaque compositions which include as an active ingredient an amino sugar containing a sugar moiety recognized by lectins on oral bacteria (e.g., .beta.-D-galactose, .beta.-D-N-acetyl galactosamine, L-rhamnose and .beta.-D-fucose) and in which nitrogen is linked to carbon number 1. The amino sugars singly or in combination with each other provide enhanced inhibition of bacterial aggregation, surfactancy, and antimicrobial activity.