Process for the preparation of taurine-conjugated bile acids
US5362891A · kind A · utility
4Cited by
2References
10Claims
0Family size
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Key dates
| Filing date | Jul 26, 1993 |
| Grant date | Nov 8, 1994 |
| Priority date | — |
| Expiry date | Jul 26, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J41/0061
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for the preparation of taurine-conjugated biliary acids of general formula (I): EQU (Y--NH--CH.sub.2 --CH.sub.2 --SO.sub.3).sub.1 M (I) where Y is the acyl of a biliary acid selected from the group consisting of ursodeoxycholic, chenodeoxycholic, lithocholic, 3.alpha.-7.beta.-12.alpha.-tri-hydroxycholanic, 3.alpha.-7.beta.-dihydroxy-12-ketocholanic, deoxycholic, dehydrocholic, iodeoxycholic, iocholic acids; M is H, Na, K, Mg, Ca; 1 is 1 or 2, being 2 when M=Mg or Ca.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.