Farnesyl pyrophosphate analogs
US5362906A · kind A · utility
6Cited by
25References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 18, 1993 |
| Grant date | Nov 8, 1994 |
| Priority date | — |
| Expiry date | Jun 18, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/3826
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to farnesyl pyrophosphate analogs which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention, and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.