Solid drug form with a high verapamil content

US5364635A · kind A · utility

Assignee

• Knoll, Inc. · DE

Inventors

• Helmut Fricke · Mutterstadt, DE
• Thomas Moest · Moorrege, DE
• Ernst Flaig · Heidelberg, DE

Key dates

• Filing date: Jul 27, 1993
• Grant date: Nov 15, 1994
• Expiry date: Jul 27, 2013

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/275
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A solid drug form containing not less than 90% by weight verapamil is produced by granulating at from 30.degree. to 55.degree. C. with a little water, drying and, where appropriate, conventional tableting or by pelleting, in which case the granules obtained as described are, after cooling, moistened once again and compacted in a granulating mixer at from 30.degree. to 55.degree. C. and are dried.