Triazole antifungal agents
US5364938A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 4, 1993 |
| Grant date | Nov 15, 1994 |
| Priority date | — |
| Expiry date | Mar 4, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides antifungal agents of the formula: ##STR1## and their pharmaceutically acceptable salts, wherein PA1 R is phenyl optionally substituted by 1 to 3 PA1 substituents each independently selected from halo and CF.sub.3 ; PA1 R.sup.1 is C.sub.1 -C.sub.4 alkyl; PA1 R.sup.2 is H or C.sub.1 -C.sub.4 alkyl; and PA1 "Het", which is attached to the adjacent carbon atom by a ring carbon atom, is selected from pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl and triazinyl, "Het" being optionally substituted by C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, halo, CF.sub.3, CN, NO.sub.2, NH.sub.2, --NH(C.sub.1 -C.sub.4 alkanoyl) or --NHCO.sub.2 (C.sub.1 -C.sub.4 alkyl).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.