Suppression of Pneumocystis carinii using aerosolized pentamidine treatment
US5366726A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 23, 1992 |
| Grant date | Nov 22, 1994 |
| Priority date | — |
| Expiry date | Jul 23, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M11/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of preventing clinically manifest Pneumocystis carinii pneumonia in immunocompromised humans is provided wherein an aerosol of pentamidine is administered to the patient in a manner which delivers the aerosol to the patient's alveoli. Also provided is a method of treating Pneumocystis carinii pneumonia in HIV seropositive individuals comprising administering a therapeutically effective amount of pentamidine aerosol to the HIV positive individual through inhalation. In addition, a method is provided of administering pentamidine to a human comprising aerosolizing a pentamidine solution in a nebulizer system having a one-way valve disposed between the nebulizer and the mouthpiece of the nebulizer system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.