Peptide production
US5366894A · kind A · utility
22Cited by
3References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 22, 1991 |
| Grant date | Nov 22, 1994 |
| Priority date | — |
| Expiry date | Nov 22, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of producing a substance comprising a peptide, involves incorporating a DNA sequence coding for the peptide into a gene of a mammal (such as a sheep) coding for a milk whey protein in such a way that the DNA sequence is expressed in the mammary gland of the adult female mammal. The substance may be an (optionally modified) protein such as a blood coagulation factor. The DNA sequence is preferably inserted into the first exon of a gene coding for a whey protein such as beta-lactoglobulin. The substance will generally be recovered from milk of the female mammal, but may (for example if it is an enzyme) be used in situ.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.