Disubstituted and deoxydisubstituted derivatives of .alpha.-d-lyxofuranosides having anti-inflammatory and anti-proliferative activity
US5367062A · kind A · utility
4Cited by
7References
12Claims
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Key dates
| Filing date | Aug 21, 1992 |
| Grant date | Nov 22, 1994 |
| Priority date | — |
| Expiry date | Aug 21, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Derivatives of disubstituted and deoxydisubstituted .alpha.-D-lyxofuranosides and intermediates for preparing these derivatives are described. These compounds exhibit significant antiinflammatory and anti-proliferative activity and are useful for treating inflammatory and/or autoimmune disorders such as psoriasis, asthma, atopic dermatitis, rheumatoid arthritis, osteoarthritis, scleroderma, systemic lupus erythematosus, and cancer (particularly melanoma and colon cancer).
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