Flow cytometer
US5367474A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1993 |
| Grant date | Nov 22, 1994 |
| Priority date | — |
| Expiry date | Feb 8, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N15/1456
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A flow cytometer includes a plurality of detectors for providing voltage pulse signals over a four decade range as particles pass through an illuminated detection station. Each voltage pulse signal is processed and provided to a first sample and hold for storage. Thereafter, the value in the first sample and hold is amplified by one or thirty-two, depending upon its magnitude, and stored in a second sample and hold for subsequent provision to a sixteen bit analog to digital convertor (ADC), one signal at a time. The first sample and hold is then free to store a new value while the old value is awaiting provision to the ADC. The ADC converts the signal received from the second sample and hold to a fifteen bit digital signal and uses the sixteenth bit to manifest whether the signal stored in the second sample and hold was amplified by thirty-two.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.