Convenient determination of trace lead in whole blood and other fluids
US5368707A · kind A · utility
37Cited by
9References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 7, 1993 |
| Grant date | Nov 29, 1994 |
| Priority date | — |
| Expiry date | Jun 7, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/817
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to methods of determining micromolar levels of lead ion in various fluids, including blood. Detection of lead or other heavy metal ion concentrations as low as 1 .mu.g/dL is achieved. The methods are adaptable to the detection of low levels of lead in whole blood, employing a novel separation and release of lead ion from lead chelating agents. The disclosed methods employ isocitrate dehydrogenase-based electrodes which are particularly suited for detecting nanomolar levels of lead.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.