Process for optical resolution of (+)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative
US5371282A · kind A · utility
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5References
4Claims
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Key dates
| Filing date | Sep 29, 1993 |
| Grant date | Dec 6, 1994 |
| Priority date | — |
| Expiry date | Sep 29, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
In optical resolution of an optically inactive (.+-.)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative into its (+)-derivative and (-)-derivative, the (.+-.)-cis-4-aminocyclopent-2-en-l-carboxylic acid derivative is allowed to react with an optically active cis-2-(arylalkylamino)cyclohexanemethanol or optically active .alpha.-alkylbenzylamine serving as an optically resolving agent, to form diastereomer salts corresponding to the (+)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative and the (-)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.