Preparation of 3-aminomethyl-3,5,5-trimethyl-cyclohexylamine

US5371292A · kind A · utility

Assignee

• BASF SE

Inventors

• Franz Merger · Bischofswerda, DE
• Claus-Ulrich Priester · Ludwigshafen, DE
• Tom Witzel · Ludwigshafen, DE
• Gerhard Koppenhoefer · Ludwigshafen, DE
• Wolfgang Harder · Weinheim, DE

Key dates

• Filing date: Jul 15, 1993
• Grant date: Dec 6, 1994
• Expiry date: Jul 15, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of 3-aminomethyl-3,5,5-trimethyl-cyclohexylamine from 3-cyano-3,5,5-trimethyl-cyclohexanone, wherein the following stages are carried out in discrete reaction chambers: PA0 a) the 3-cyano-3,5,5-trimethyl-cyclohexanone is reacted in a first reaction chamber with excess ammonia over an acidic metal oxide catalyst at a temperature of from 20.degree. to 150.degree. C. and a pressure of from 15 to 500 bar, and PA0 b) in a second reaction chamber, the reaction product from stage a) is hydrogenated with hydrogen at a temperature of from 60.degree. to 150.degree. C. and a pressure of from 50 to 300 bar in the presence of excess ammonia over a catalyst containing cobalt, nickel, ruthenium, and/or some other noble metal, which catalyst optionally contains a basic component or is supported by neutral or basic supporting material.