Biological stain composition, method of preparation and method of use for delineation of epithelial cancer
US5372801A · kind A · utility
11Cited by
6References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 7, 1993 |
| Grant date | Dec 13, 1994 |
| Priority date | — |
| Expiry date | Jun 7, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N1/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A biological stain composition contains toluidine blue O and a pharmaceutically acceptable oxidizing agent to convert any leuco toluidine blue O to the chromo form. A dry composition for preparing the stain includes the toluidine blue O, the oxidizing agent and an effervescent agent. These compositions are preferably buffered to improve shelf stability and clinical consistency. Compositions for intra-oral application contain a flavoring agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.