Patent · US Expired

Memory enhancing thermal proteins

US5373085A · kind A · utility

4Cited by
2References
2Claims
0Family size

Inventors

Key dates

Filing dateSep 28, 1992
Grant dateDec 13, 1994
Priority date
Expiry dateSep 28, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08G69/10
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Memory enhancing thermal proteins were synthesized from heating aspartic acid, glutamic acid, proline and tryptophan above 100.degree. C. Two hydrophobic and one non-hydrophobic polymer were injected intracerebroventricularly into the brains of mice after the mice had undergone partial training in footshock avoidance conducted in a T-maze. When retention of footshock avoidance was tested one week later, the hydrophobic polymers enhanced retention while the non-hydrophobic polymer did not.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.