Memory enhancing thermal proteins
US5373085A · kind A · utility
Inventors
Key dates
| Filing date | Sep 28, 1992 |
| Grant date | Dec 13, 1994 |
| Priority date | — |
| Expiry date | Sep 28, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G69/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Memory enhancing thermal proteins were synthesized from heating aspartic acid, glutamic acid, proline and tryptophan above 100.degree. C. Two hydrophobic and one non-hydrophobic polymer were injected intracerebroventricularly into the brains of mice after the mice had undergone partial training in footshock avoidance conducted in a T-maze. When retention of footshock avoidance was tested one week later, the hydrophobic polymers enhanced retention while the non-hydrophobic polymer did not.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.