Implantable active substance depot material

US5374427A · kind A · utility

Assignee

• Thera Patent GmbH & Co. KG · DE

Inventors

• Wolfgang Stille · Frankfurt am Main, DE
• Gabriele Gentschew · Frankfurt am Main, DE
• Peter Reitz · Obertshausen, DE
• Thomas Erben · Eichberg, CH
• Werner Zollner · Eitting, DE
• Klaus-Peter Stefan · Hanerau-Hademarschen, DE

Key dates

• Filing date: Dec 10, 1992
• Grant date: Dec 20, 1994
• Expiry date: Dec 10, 2012

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2300/416
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An implantable active substance depot material which contains a glass ionomer cement and one or more chemotherapeutic agents. The active substance depot materials ensure an initially high release rate of the active substance therein and subsequently a discharge of the active substance in small doses until complete depletion of the deposited active substance has occurred.