Six membered ring fused imidazoles substituted with phenoxyphenylacetic acid derivatives used to treat asthma
US5374638A · kind A · utility
26Cited by
6References
6Claims
0Family size
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Key dates
| Filing date | Mar 19, 1993 |
| Grant date | Dec 20, 1994 |
| Priority date | — |
| Expiry date | Mar 19, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Phenoxyphenylacetic acids and derivatives of general structural formula I ##STR1## have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, congestive heart failure, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, inflammatory diseases, Raynaud's disease, and endotoxic shock, and asthma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.