Benzofuran derivatives
US5374646A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 15, 1993 |
| Grant date | Dec 20, 1994 |
| Priority date | — |
| Expiry date | Mar 15, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides compounds of the general formula (I) ##STR1## and physiologically acceptable salts, solvates or non-toxic metabolically labile esters thereof where R.sup.1 represents a halogen atom; Ar represents the group ##STR2## R.sup.3 represents a C-linked tetrazolyl group; R.sup.4 and R.sup.5, which may be the same or different, each independently represent a hydrogen atom or a halogen atom or a C.sub.1-6 alkyl group; and PA1 Het represents an N-linked imidazolyl group optionally substituted at the 2-position. The compounds may be used in the treatment or prophylaxis of hypertension and diseases associated with cognitive disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.