Method for enhancing the lowering of plasma-cholesterol levels
US5376383A · kind A · utility
7Cited by
23References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 1, 1993 |
| Grant date | Dec 27, 1994 |
| Priority date | — |
| Expiry date | Feb 1, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/365
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The instant invention is directed to a method for enhancing the lowering of plasma cholesterol level in a subject in need thereof which comprises the time-controlled administration of a nontoxic therapeutically effective amount of an HMG-CoA reductase inhibitor to said subject which surprisingly affords an equivalent or improved reduction of plasma cholesterol levels while significantly reducing the amount of HMG-CoA reductase inhibitor circulating in the bloodstream of the subject as compared to the same parameters when the oral administration of a conventional rapid release dosage form is utilized.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.