Triglyceride oils labelled with .sup.13 C prepared by cultivation of microorganisms
US5376540A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Sep 24, 1992 |
| Grant date | Dec 27, 1994 |
| Priority date | — |
| Expiry date | Sep 24, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/946
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Labelled triglyceride oils are produced for use in diagnostic breath tests. The process involves the cultivation of microorganisms capable of producing the oils in an appropriately controlled environment wherein the microorganisms are feed .sup.13 C or .sup.14 C labeled carbon substrates to induce the microorganisms to produce the labeled oils. The preferred labelled carbon substrate is a substrate containing .sup.13 C. The oil produced is preferrably enriched in oleic acid. The microorganisms can be induced to produce the oil by nitrogen depletion during cultivation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.