Method of detecting hepatitis B variants having deletions within the X region of the virus genome
US5378605A · kind A · utility
2Cited by
1References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 8, 1993 |
| Grant date | Jan 3, 1995 |
| Priority date | — |
| Expiry date | Jun 8, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/706
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods for the detection of hepatitis B virus in atypical infections by simultaneously detecting antibodies against the X and polymerase gene products of HBV. Further, the present invention provides methods for the detection of HBV in atypical infections in a polymerase chain reaction (PCR) assay employing selected primes. These primers allow the detection of a specific class of HBV variants. These methods are useful for demonstrating the presence of productive virus infection and may prove useful in monitoring therapeutics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.