Process for the preparation of ergoline derivatives
US5382669A · kind A · utility
9Cited by
0References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 9, 1993 |
| Grant date | Jan 17, 1995 |
| Priority date | — |
| Expiry date | Mar 9, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a process for the preparation of ergoline derivatives of the formula I ##STR1## the process comprising reacting an ergoline amide of the formula II with an isocyanate of formula III ##STR2## in presence of a metal catalyst and of a phosphorus compound. The compounds of the formula I are useful antiprolactinic and antiparkinson agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.