Pellets containing dihydropyridine derivatives process for the production thereof and use as rapid action dosage in heart and circulatory diseases

US5384129A · kind A · utility

Assignee

• ALFATEC-Pharm GmbH · DE

Inventors

• Jens-Christian Wunderlich · Heidelberg, DE
• Ursula Schick · Schriesheim, DE
• Jurgen Freidenreich · Schriesheim, DE
• Jurgen Werry · Ludwigshafen, DE

Key dates

• Filing date: Apr 30, 1992
• Grant date: Jan 24, 1995
• Expiry date: Apr 30, 2012

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/1658
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is directed to dihydropyridine derivative containing pellets comprising a dispersion of the dihydropyridine derivatives in a matrix which is substantially formed of a skeleton builder such as gelatin, fractionated gelatin, a collagen hydrolysate and/or a gelatin derivative. The invention further directs to a process for the preparation of dihydropyridine derivative containing pellets as well as their use as acute dosage forms against heart/circulatory illnesses.