PO438, a new calcium-regulated promoter
US5385841A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 11, 1992 |
| Grant date | Jan 31, 1995 |
| Priority date | — |
| Expiry date | Dec 11, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
There is disclosed a new calcium-regulated promoter to be used for increasing production of extracellular enzymes, or heterologous polypeptides, a recombinant vector that includes the DNA sequence of the promoter operatively linked to a DNA encoding said enzyme or polypeptide and a host organism transformed with the recombinant vector that includes the promoter operatively linked to the DNA encoding said enzyme or polypeptide. The present invention further relates to Streptomyces expression systems and methods for expressing foreign DNA sequences in Streptomyces and for secreting to the surrounding medium polypeptides and proteins coded for by those foreign DNA sequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.