Aminomethylene-peptides as immunosuppressants

US5385918A · kind A · utility

Assignee

• Miles Inc. · US

Inventors

• Richard Connell · Trumbull, US
• David Osterman · Glastonbury, US
• Michael Katz · Wallingford, US
• Rudolf Hanko · Düsseldorf, DE
• Stephan Schneider · Wuppertal, DE

Key dates

• Filing date: Feb 9, 1993
• Grant date: Jan 31, 1995
• Expiry date: Feb 9, 2013

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds which suppress human T-lymphocyte proliferation are disclosed. The active compounds essentially contain at least the following structure: ##STR1## wherein A, R.sup.1, R.sup.2, R.sup.3, n, X.sup.1 and Z are defined in the specification.