Patent · US Expired

Sulfonamides derived from benzocyclic or benzoheterocyclic acids, their preparation and application in therapeutics

US5385931A · kind A · utility

20Cited by
4References
33Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 28, 1990
Grant dateJan 31, 1995
Priority date
Expiry dateDec 28, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2602/08
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to new sulphonamide derivatives of benzo-cyclic or benzo-heterocyclic acids and their derivatives of general formula I ##STR1## in which: R represents a straight-chain or branched lower alkyl radical having 1 to 9 C; a phenyl radical which is unsubstituted or substituted by one or more groups: PA1 straight-chain or branched lower alkyl having 1 to 4 C, halogeno, alkoxy, nitro, amino, dialkylamino or CF.sub.3 ; PA1 a substituted or unsubstituted naphthalene; PA1 a thiophenyl radical; PA1 R.sub.1 represents a hydrogen or a straight-chain or branched lower alkyl or a benzyl; PA1 R.sub.2 represents a hydrogen, a straight-chain or branched lower alkyl group, a substituted or unsubstituted phenyl group or an aralkyl group; PA1 R.sub.3 represents a hydrogen or a straight-chain or branched lower alkyl (1 to 6 C); PA1 --X-- represents a divalent functional radical chosen from the following: --CH.sub.2 --; ##STR2## where R.sub.4 =H or Me; A represents a benzo-cyclic or benzo-heterocyclic divalent radical chosen from the following (a) to (j): ##STR3## and n can assume the values 1 to 4 inclusive; and the therapeutically acceptable organic or inorganic salts (R.sub.3 =H),…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.