Process for the production of N-.beta.-hydroxyalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecane and N-.beta.-hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradeca ne derivatives and their metal complexes

US5386028A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Ulf Tilstam · Berlin, DE
• Helmut Borner · Berlin, DE
• Klaus Nickisch · Berlin, DE
• Heinz Gries · Berlin, DE
• Johannes Platzek · Berlin, DE

Key dates

• Filing date: Feb 11, 1993
• Grant date: Jan 31, 1995
• Expiry date: Feb 11, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D257/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the production of N-.beta.-hydroxyalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecane and N-.beta.-hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetrade cane derivatives and their metal complexes is described.