Method for enhancing magnetic resonance with compositions containing paramagnetic elements carried by liposomes
US5387410A · kind A · utility
17Cited by
8References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 15, 1989 |
| Grant date | Feb 7, 1995 |
| Priority date | — |
| Expiry date | Feb 15, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Nuclear magnetic resonance (NMR) imaging of body organs and tissues is enhanced by administering to a living animal body a substantially nontoxic paramagnetic image altering agent comprised of a composition containing a chelate of a paramagnetic element, such as manganese, gadolinium or iron, carried by a liposome. The chelate is carried by or within the external surface of the liposome in such a manner that after arrival at or delivery to the desired organ or tissue site, the paramagnetic image altering agent is released in a diagnostically useful fashion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.