C-22 ring stabilized rapamycin derivatives
US5387680A · kind A · utility
62Cited by
22References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 10, 1993 |
| Grant date | Feb 7, 1995 |
| Priority date | — |
| Expiry date | Aug 10, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides C-22 substituted rapamycin derivatives of the following formulas: ##STR1## and pharmaceutically acceptable salts thereof which are useful for inducing immunosuppression and treating transplantation rejection, host vs. graft disease, autoimmune diseases, diseases of inflammation, solid tumors, fungal infections, adult T-cell leukemia/lymphomas and hyperproliferative vascular disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.