Compounds and methods for generating oxygen free radicals used in general oxidation and reduction reactions
US5389356A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 5, 1993 |
| Grant date | Feb 14, 1995 |
| Priority date | — |
| Expiry date | Jan 5, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S588/901
- WIPO fieldEnvironmental technology
- WIPO sectorChemistry
Abstract
Composition and methods for carrying out a variety of oxidation reactions, reduction reactions, or both utilizing a free radical generating catalyst, a mediator, and a reductant are disclosed, The free radical generating catalyst is generally a peroxidase obtained from living organisms, such as white rot fungi. Suitable peroxidases include lignin peroxidase, horse radish peroxidase, and lactoperoxidase. Suitable mediators include veratryl alcohol, iodine, methoxybenzenes, Mn II, and ABTS. Suitable reductants include EDTA, oxalate, hydroquinones, quinones plus quinone reductase, and hydrogen peroxide. The free radical generating catalyst is generally activated in the presence of hydrogen peroxide and reacts with the mediator to form the free radical of the mediator, which is an oxidant. The free radical of the mediator in turn reacts with the reductant to form the free radical of the reductant, which is also a reductant. The free radical oxidants and reductants can react directly with targeted substrates to carry out either oxidation or reduction reactions, or they can further react in other intermediate reactions to form additional oxidants and reductants. Targeted substrates inclu…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.