Purification of heparinase I, II, and III from Flavobacterium heparinum
US5389539A · kind A · utility
25Cited by
6References
8Claims
0Family size
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Key dates
| Filing date | Nov 30, 1992 |
| Grant date | Feb 14, 1995 |
| Priority date | — |
| Expiry date | Nov 30, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/85
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A purified heparinase I, II and III free of lyase activity and each having a molecular weight of 42,800 84,100, 70,800, respectively, are produced by culturing Flavobacterium heparinum. The kinetic properties of the heparinases have been determined as well as the conditions to optimize their activity and stability.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.