Imidazole and 1,2,4-triazole derivatives with angiotensin II antagonist properties
US5389661A · kind A · utility
25Cited by
3References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 10, 1994 |
| Grant date | Feb 14, 1995 |
| Priority date | — |
| Expiry date | Feb 10, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to novel substituted imidazole and triazole derivatives which antagonize the binding of angiotensin II to its receptors. The compounds are useful in the treatment of hypertension, heart failure, glaucoma, and hyperaldosteronism. Methods of making the compounds, novel intermediates useful in the preparation of the compounds, pharmaceutical compositions containing the compounds, and methods of using them are also covered.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.