Fused benzeneoxyacetic acid derivatives
US5389666A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 28, 1992 |
| Grant date | Feb 14, 1995 |
| Priority date | — |
| Expiry date | Dec 28, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A fused benzeneoxyacetic acid derivative of the formula (I): ##STR1## R.sup.1 is OH, alkoxy, (alkyl)amino, residue of an amino acid; A is phenyl, alkyl substituted by phenyl, residue of an imidazole, imidazole-2-yloxy(thio), 2-oxoimidazole, pyrazole, oxadiazole, oxazole, triazole, isoxazole or isothiazole, in the group of benzene may be substituted by one to three of alkyl, alkoxy, halogen, nitro or trihalomethyl; PA1 e is 3-5; PA1 f is 1-3; PA1 p is 1-4; PA1 q is 0-2; PA1 r is 1-4; PA1 s is 0-3) and salts thereof possess an agonistic on PGI.sub.2 receptor, so it is useful for prevention and/or treatment of thrombosis, arteriosclerosis, inchemic heart diseases, gastric alcer and hypertention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.