Method for performing a solid-phase extraction under pressurized conditions
US5391298A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 5, 1993 |
| Grant date | Feb 21, 1995 |
| Priority date | — |
| Expiry date | Mar 5, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N1/405
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A method of performing a solid phase extraction on an aqueous fluid using a hydrophobic, solid-phase extraction medium (40), which method comprises: (a) placing (10) a hydrophobic, solid-phase extraction medium (40) inside of a pressurizable housing (18) having an inlet (25) and an outlet (32), the hydrophobic, solid-phase extraction medium (40) being positioned in the pressurizable housing (18) such that a liquid moving from the inlet (25) to the outlet (32) passes through the solid-phase extraction medium (40); (b) priming (12) the hydrophobic, solid-phase extraction medium (40) with a water-miscible organic liquid by passing the water-miscible organic liquid from the inlet (25) to the outlet (32) under positive pressure; and (c) passing (14) an aqueous liquid from the inlet (25) to the outlet (32) under positive pressure; wherein the water-miscible organic liquid and aqueous liquid are passed from the inlet (25) to the outlet (32) such that the solid-phase extraction medium (40) is completely and continuously immersed in liquid in the pressurizable housing (18) during steps (b) and (c).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.